Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage

The stability and function of eukaryotic genomes is closely linked to histones and to chromatin structure. The state of the chromatin not only affects the probability of DNA to undergo damage but also DNA repair. DNA damage can result in genetic alterations and subsequent development of cancer and o...

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Publicado en:Microb Cell
Autores principales: Ortega, Pedro, García-Pichardo, Desiré, San Martin-Alonso, Marta, Rondón, Ana G., Gómez-González, Belén, Aguilera, Andrés
Formato: Artigo
Lenguaje:Inglês
Publicado: Shared Science Publishers OG 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328676/
https://ncbi.nlm.nih.gov/pubmed/32656258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2020.07.723
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