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Partial Depletion of Histone H4 Increases Homologous Recombination-Mediated Genetic Instability

DNA replication can be a source of genetic instability. Given the tight connection between DNA replication and nucleosome assembly, we analyzed the effect of a partial depletion of histone H4 on genetic instability mediated by homologous recombination. A Saccharomyces cerevisiae strain was construct...

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Detalhes bibliográficos
Main Authors: Prado, Félix, Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548009/
https://ncbi.nlm.nih.gov/pubmed/15684401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.4.1526-1536.2005
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