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Cancer Stem Cells and Epithelial-to-Mesenchymal Transition in Cancer Metastasis

The cancer stem cell (CSC) concept stands for undifferentiated tumor cells with the ability to initiate heterogeneous tumors. It is also relevant in metastasis and can explain how metastatic tumors mirror the heterogeneity of primary tumors. Cellular plasticity, including the epithelial-to-mesenchym...

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Pubblicato in:Cold Spring Harb Perspect Med
Autori principali: Celià-Terrassa, Toni, Jolly, Mohit Kumar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328448/
https://ncbi.nlm.nih.gov/pubmed/31570380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036905
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