Highly efficient generation of sheep with a defined FecB(B) mutation via adenine base editing

Base editing has the potential to improve important economic traits in agriculture and can precisely convert single nucleotides in DNA or RNA sequences into minimal double-strand DNA breaks (DSB). Adenine base editors (ABE) have recently emerged as a base editing tool for the conversion of targeted...

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Detalhes bibliográficos
Publicado no:Genet Sel Evol
Main Authors: Zhou, Shiwei, Ding, Yige, Liu, Jiao, Liu, Yao, Zhao, Xiaoe, Li, Guanwei, Zhang, Chenguang, Li, Chao, Wang, Ying, Kalds, Peter, Gao, Yawei, Zong, Bo, Huang, Xiaoyu, Huang, Shuhong, Yu, Honghao, Kou, Qifang, Petersen, Bjoern, Huang, Xingxu, Wang, Xiaolong, Ma, Baohua, Chen, Yulin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328262/
https://ncbi.nlm.nih.gov/pubmed/32611306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-020-00554-6
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