Highly efficient generation of sheep with a defined FecB(B) mutation via adenine base editing

Base editing has the potential to improve important economic traits in agriculture and can precisely convert single nucleotides in DNA or RNA sequences into minimal double-strand DNA breaks (DSB). Adenine base editors (ABE) have recently emerged as a base editing tool for the conversion of targeted...

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Dades bibliogràfiques
Publicat a:Genet Sel Evol
Autors principals: Zhou, Shiwei, Ding, Yige, Liu, Jiao, Liu, Yao, Zhao, Xiaoe, Li, Guanwei, Zhang, Chenguang, Li, Chao, Wang, Ying, Kalds, Peter, Gao, Yawei, Zong, Bo, Huang, Xiaoyu, Huang, Shuhong, Yu, Honghao, Kou, Qifang, Petersen, Bjoern, Huang, Xingxu, Wang, Xiaolong, Ma, Baohua, Chen, Yulin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328262/
https://ncbi.nlm.nih.gov/pubmed/32611306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-020-00554-6
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