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A Drosophila model to study retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8

Retinitis pigmentosa (RP) represents genetically heterogeneous and clinically variable disease characterized by progressive degeneration of photoreceptors resulting in a gradual loss of vision. The autosomal dominant RP type 13 (RP13) has been linked to the malfunction of PRPF8, an essential compone...

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Bibliographische Detailangaben
Veröffentlicht in:Dis Model Mech
Hauptverfasser: Stanković, Dimitrije, Claudius, Ann-Katrin, Schertel, Thomas, Bresser, Tina, Uhlirova, Mirka
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328144/
https://ncbi.nlm.nih.gov/pubmed/32424050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.043174
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