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Opposing effects of an F-box protein and the HSP90 chaperone network on microtubule stability and neurite growth in Caenorhabditis elegans

Molecular chaperones often work collaboratively with the ubiquitylation-proteasome system (UPS) to facilitate the degradation of misfolded proteins, which typically safeguards cellular differentiation and protects cells from stress. In this study, however, we report that the Hsp70/Hsp90 chaperone ma...

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Библиографические подробности
Опубликовано в: :Development
Главные авторы: Zheng, Chaogu, Atlas, Emily, Lee, Ho Ming Terence, Jao, Susan Laura Javier, Nguyen, Ken C. Q., Hall, David H., Chalfie, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328132/
https://ncbi.nlm.nih.gov/pubmed/32467239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.189886
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