Liver-specific ceramide reduction alleviates steatosis and insulin resistance in alcohol-fed mice

Alcohol’s impairment of both hepatic lipid metabolism and insulin resistance (IR) are key drivers of alcoholic steatosis, the initial stage of alcoholic liver disease (ALD). Pharmacologic reduction of lipotoxic ceramide prevents alcoholic steatosis and glucose intolerance in mice, but potential off-...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Lipid Res
Main Authors: Correnti, Jason, Lin, Chelsea, Brettschneider, Jascha, Kuriakose, Amy, Jeon, Sookyoung, Scorletti, Eleonora, Oranu, Amanke, McIver-Jenkins, Dru, Kaneza, Isabelle, Buyco, Delfin, Saiman, Yedidya, Furth, Emma E., Argemi, Josepmaria, Bataller, Ramon, Holland, William L., Carr, Rotonya M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328039/
https://ncbi.nlm.nih.gov/pubmed/32398264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000446
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker