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Ferrous but not ferric iron sulfate kills photoreceptors and induces photoreceptor-dependent RPE autofluorescence

Iron has been implicated in the pathogenesis of retinal degenerative diseases, including ocular siderosis. However, the mechanisms of iron-induced retinal toxicity are incompletely understood. Previous work shows that intravitreal injection of Fe(2+) leads to photoreceptor (PR) oxidative stress, res...

詳細記述

保存先:
書誌詳細
出版年:Redox Biol
主要な著者: Shu, Wanting, Baumann, Bailey H., Song, Ying, Liu, Yingrui, Wu, Xingwei, Dunaief, Joshua L.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327978/
https://ncbi.nlm.nih.gov/pubmed/32362442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101469
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