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The impact of pre-existing HLA and red blood cell antibodies on transfusion support and engraftment in sickle cell disease after nonmyeloablative hematopoietic stem cell transplantation from HLA-matched sibling donors: A prospective, single-center, observational study

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is curative for patients with sickle cell disease (SCD). Prior to HSCT, patients with SCD commonly receive RBC transfusions with some becoming RBC or HLA alloimmunized. This alloimmunization may impact post-HSCT transfusion requirements and...

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書誌詳細
出版年:EClinicalMedicine
主要な著者: Nickel, Robert Sheppard, Flegel, Willy A., Adams, Sharon D., Hendrickson, Jeanne E., Liang, Hua, Tisdale, John F., Hsieh, Matthew M.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327930/
https://ncbi.nlm.nih.gov/pubmed/32637902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eclinm.2020.100432
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