Cytoplasmic, but not nuclear Nrf2 expression, is associated with inferior survival and relapse rate and response to platinum‐based chemotherapy in non‐small cell lung cancer

BACKGROUND: Several studies have previously indicated that nuclear factor erythroid 2‐related factor 2 (Nrf2) expression may promote tumor progression when the Keap1/Nrf2 pathway is activated, but few reports have demonstrated the role of cytoplasmic Nrf2 on tumorigenesis. METHODS: Immunohistochemis...

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Bibliografiske detaljer
Udgivet i:Thorac Cancer
Main Authors: Chen, Ming‐Jenn, Lin, Po‐Lin, Wang, Lee, Cheng, Ya‐Min, Chen, Chih‐Yi, Lee, Huei
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons Australia, Ltd 2020
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327683/
https://ncbi.nlm.nih.gov/pubmed/32394538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13479
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