Resveratrol activates DNA damage response through inhibition of polo-like kinase 1 (PLK1) in natural killer/T cell lymphoma

BACKGROUND: Extranodal natural killer/T cell lymphoma (NKTCL) is a highly aggressive non-Hodgkin lymphoma with a poor prognosis. Resveratrol (REV), a natural nontoxic pleiotropic agent, has antitumor effects, yet not being studied in NKTCL. METHODS: We performed immunohistochemical (IHC) staining wi...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Sui, Xianxian, Zhang, Canjing, Jiang, Yudong, Zhou, Jianan, Xu, Chen, Tang, Feng, Chen, Bobin, Xu, Huiwen, Wang, Songmei, Wang, Xuanyi
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327334/
https://ncbi.nlm.nih.gov/pubmed/32617308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-19-4324
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