Pharmacokinetics and bioequivalence of fixed-dose combination of candesartan cilexetil/amlodipine besylate (16/10 mg) versus coadministration of individual formulations in healthy subjects

This study compared the pharmacokinetics of a fixed-dose combination (FDC) of candesartan (16 mg) and amlodipine (10 mg) versus coadministration of individual formulations to clarify the bioequivalence of the FDC. In this randomized, open-label, single-dose, 2-treatment, 2-way crossover study, healt...

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Detalhes bibliográficos
Publicado no:Transl Clin Pharmacol
Main Authors: Lee, Hae Won, Kang, Woo Youl, Jung, Wookjae, Gwon, Mi-Ri, Yang, Dong Heon, Kim, Eun Hee, Cho, Kyunghee, Yoon, Young-Ran, Seong, Sook Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Clinical Pharmacology and Therapeutics 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327189/
https://ncbi.nlm.nih.gov/pubmed/32656160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2020.28.e8
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