Development and Evaluation of a Modified Fixed-Dose Combination Antihypertensive Tablet Containing S-Amlodipine Besylate: A Bioequivalence and Stability Study

<b>Background</b>/<b>Objectives</b>: Fixed-dose combination (FDC) antihypertensive medications containing olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide are widely used for the treatment of essential hypertension. Although effective, the use of racemic amlodipine, which contains...

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Autori principali:	Hyeon Woo Moon, Jin-Hyuk Jeong, Chun-Woong Park
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-09-01
Serie:	Pharmaceutics
Soggetti:	S-amlodipine besylate olmesartan medoxomil hydrochlorothiazide fixed-dose combination bilayer tablet stability
Accesso online:	https://www.mdpi.com/1999-4923/17/9/1235
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