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Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds

Trauma-related necrotizing myocutaneous mucormycosis (NMM) has a high morbidity and mortality in victims of combat-related injuries, geometeorological disasters, and severe burns. Inspired by the observation that several recent clusters of NMM have been associated with extreme mechanical forces (e.g...

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Bibliografiset tiedot
Julkaisussa:mBio
Päätekijät: Wurster, Sebastian, Tatara, Alexander M., Albert, Nathaniel D., Ibrahim, Ashraf S., Heitman, Joseph, Lee, Soo Chan, Shetty, Amol C., McCracken, Carrie, Graf, Karen T., Mikos, Antonios G., Bruno, Vincent M., Kontoyiannis, Dimitrios P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327176/
https://ncbi.nlm.nih.gov/pubmed/32605990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01414-20
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