Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds

Trauma-related necrotizing myocutaneous mucormycosis (NMM) has a high morbidity and mortality in victims of combat-related injuries, geometeorological disasters, and severe burns. Inspired by the observation that several recent clusters of NMM have been associated with extreme mechanical forces (e.g...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Wurster, Sebastian, Tatara, Alexander M., Albert, Nathaniel D., Ibrahim, Ashraf S., Heitman, Joseph, Lee, Soo Chan, Shetty, Amol C., McCracken, Carrie, Graf, Karen T., Mikos, Antonios G., Bruno, Vincent M., Kontoyiannis, Dimitrios P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327176/
https://ncbi.nlm.nih.gov/pubmed/32605990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01414-20
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