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Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in in vitro and in vivo preclinical models

Tissue fibrosis underlies the majority of human mortality to date with close to half of all reported deaths having a fibrotic etiology. The progression of fibrosis is very complex and reputed irreversible once established. Although some preventive options are being reported, therapeutic options are...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Nono, Justin Komguep, Fu, Kai, Mpotje, Thabo, Varrone, Georgianna, Aziz, Nada Abdel, Mosala, Paballo, Hlaka, Lerato, Kamdem, Severin Donald, Xu, Daigen, Spangenberg, Thomas, Brombacher, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327036/
https://ncbi.nlm.nih.gov/pubmed/32606340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67514-4
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