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The Foxp3(+) regulatory T-cell population requires IL-4Rα signaling to control inflammation during helminth infections
Forkhead box P3 (Foxp3(+)) regulatory T (Treg)-cell function is controlled by environmental cues of which cytokine-mediated signaling is a dominant component. In vivo, interleukin-4 (IL-4)-mediated signaling via IL-4 receptor alpha (IL-4Rα) mediates Treg cell transdifferentiation into ex-Foxp3 T hel...
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| Publicado no: | PLoS Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6231676/ https://ncbi.nlm.nih.gov/pubmed/30379806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005850 |
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