HA stabilization promotes replication and transmission of swine H1N1 gamma influenza viruses in ferrets

Pandemic influenza A viruses can emerge from swine, an intermediate host that supports adaptation of human-preferred receptor-binding specificity by the hemagglutinin (HA) surface antigen. Other HA traits necessary for pandemic potential are poorly understood. For swine influenza viruses isolated in...

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Pubblicato in:eLife
Autori principali: Hu, Meng, Yang, Guohua, DeBeauchamp, Jennifer, Crumpton, Jeri Carol, Kim, Hyunsuh, Li, Lei, Wan, Xiu-Feng, Kercher, Lisa, Bowman, Andrew S, Webster, Robert G, Webby, Richard J, Russell, Charles J
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
Soggetti:
Microbiology and Infectious Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326494/
https://ncbi.nlm.nih.gov/pubmed/32602461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56236
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