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H1N1 influenza viruses varying widely in hemagglutinin stability transmit efficiently from swine to swine and to ferrets

A pandemic-capable influenza virus requires a hemagglutinin (HA) surface glycoprotein that is immunologically unseen by most people and is capable of supporting replication and transmission in humans. HA stabilization has been linked to 2009 pH1N1 pandemic potential in humans and H5N1 airborne trans...

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Опубликовано в: :PLoS Pathog
Главные авторы: Russier, Marion, Yang, Guohua, Marinova-Petkova, Atanaska, Vogel, Peter, Kaplan, Bryan S., Webby, Richard J., Russell, Charles J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362248/
https://ncbi.nlm.nih.gov/pubmed/28282440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006276
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