Generation of inner ear hair cells by direct lineage conversion of primary somatic cells

The mechanoreceptive sensory hair cells in the inner ear are selectively vulnerable to numerous genetic and environmental insults. In mammals, hair cells lack regenerative capacity, and their death leads to permanent hearing loss and vestibular dysfunction. Their paucity and inaccessibility has limi...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Menendez, Louise, Trecek, Talon, Gopalakrishnan, Suhasni, Tao, Litao, Markowitz, Alexander L, Yu, Haoze V, Wang, Xizi, Llamas, Juan, Huang, Chichou, Lee, James, Kalluri, Radha, Ichida, Justin, Segil, Neil
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2020
Konular:
Developmental Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326493/
https://ncbi.nlm.nih.gov/pubmed/32602462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55249
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