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AMPK Preferentially Depresses Retrograde Transport of Axonal Mitochondria during Localized Nutrient Deprivation

Mitochondrial clusters are found at regions of high-energy demand, allowing cells to meet local metabolic requirements while maintaining neuronal homeostasis. AMP-activated protein kinase (AMPK), a key energy stress sensor, responds to increases in AMP/ATP ratio by activating multiple signaling casc...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Watters, Orla, Connolly, Niamh M. C., König, Hans-Georg, Düssmann, Heiko, Prehn, Jochen H. M.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326360/
https://ncbi.nlm.nih.gov/pubmed/32393534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2067-19.2020
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