AMPK Preferentially Depresses Retrograde Transport of Axonal Mitochondria during Localized Nutrient Deprivation

Mitochondrial clusters are found at regions of high-energy demand, allowing cells to meet local metabolic requirements while maintaining neuronal homeostasis. AMP-activated protein kinase (AMPK), a key energy stress sensor, responds to increases in AMP/ATP ratio by activating multiple signaling casc...

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Pubblicato in:J Neurosci
Autori principali: Watters, Orla, Connolly, Niamh M. C., König, Hans-Georg, Düssmann, Heiko, Prehn, Jochen H. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326360/
https://ncbi.nlm.nih.gov/pubmed/32393534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2067-19.2020
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