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Generation of a glycosylated asparagine residue through chemoselective acylation of a glycosylhydrazide

Herein, we report the first selective anomeric N-acylation of a glycosylhydrazide. We show that this transformation can be harnessed to generate amino acid building blocks including FmocAsn(GlcNAc)OH (1), a residue that has been previously shown to be a competent reagent in the solid-phase peptide s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Carbohydr Res
Egile Nagusiak: Rykaczewski, Katie A., Sabourin, Kate E., Goo, Paul J., Griggs, Lydia H., Jain, Saumya, Reed, Paxton A. M., Langenhanmi, Joseph M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325706/
https://ncbi.nlm.nih.gov/pubmed/32516600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2020.108022
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