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Generation of a glycosylated asparagine residue through chemoselective acylation of a glycosylhydrazide
Herein, we report the first selective anomeric N-acylation of a glycosylhydrazide. We show that this transformation can be harnessed to generate amino acid building blocks including FmocAsn(GlcNAc)OH (1), a residue that has been previously shown to be a competent reagent in the solid-phase peptide s...
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| Publicado no: | Carbohydr Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7325706/ https://ncbi.nlm.nih.gov/pubmed/32516600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2020.108022 |
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