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A role for PGC-1α in transcription and excitability of neocortical and hippocampal excitatory neurons

The transcriptional coactivator peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is a critical regulator of genes involved in neuronal metabolism, neurotransmission, and morphology. Reduced PGC-1α expression has been implicated in several neurological and psychiatric disorders. A...

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Publicat a:Neuroscience
Autors principals: McMeekin, LJ, Bartley, AF, Bohannon, AS, Adlaf, EW, van Groen, T, Boas, SM, Fox, SN, Detloff, PJ, Crossman, DK, Overstreet-Wadiche, LS, Hablitz, JJ, Dobrunz, LE, Cowell, RM
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325608/
https://ncbi.nlm.nih.gov/pubmed/32222555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2020.03.036
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