Trial of intrathecal rituximab in progressive multiple sclerosis patients with evidence of leptomeningeal contrast enhancement

BACKGROUND: Leptomeningeal inflammation is associated with increased cortical damage and worse clinical outcomes in MS. It may be detected on contrast-enhanced T2-FLAIR imaging as focal leptomeningeal contrast-enhancement (LME). OBJECTIVE: To assess the safety of intrathecal (IT) rituximab in progre...

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Detalhes bibliográficos
Publicado no:Mult Scler Relat Disord
Main Authors: Bhargava, Pavan, Wicken, Cassie, Smith, Matthew D, Strowd, Roy E., Cortese, Irene, Reich, Daniel S, Calabresi, Peter A, Mowry, Ellen M
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325522/
https://ncbi.nlm.nih.gov/pubmed/30771580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.msard.2019.02.013
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