Immunopeptidomic Data Integration to Artificial Neural Networks Enhances Protein-Drug Immunogenicity Prediction

Recombinant DNA technology has, in the last decades, contributed to a vast expansion of the use of protein drugs as pharmaceutical agents. However, such biological drugs can lead to the formation of anti-drug antibodies (ADAs) that may result in adverse effects, including allergic reactions and comp...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Barra, Carolina, Ackaert, Chloe, Reynisson, Birkir, Schockaert, Jana, Jessen, Leon Eyrich, Watson, Mark, Jang, Anne, Comtois-Marotte, Simon, Goulet, Jean-Philippe, Pattijn, Sofie, Paramithiotis, Eustache, Nielsen, Morten
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325480/
https://ncbi.nlm.nih.gov/pubmed/32655572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01304
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