A Novel E2F1-EP300-VMP1 Pathway Mediates Gemcitabine-Induced Autophagy in Pancreatic Cancer Cells Carrying Oncogenic KRAS

Autophagy is an evolutionarily preserved degradation process of cytoplasmic cellular constituents, which participates in cell response to disease. We previously characterized VMP1 (Vacuole Membrane Protein 1) as an essential autophagy related protein that mediates autophagy in pancreatic diseases. W...

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Detalles Bibliográficos
Publicado en:Front Endocrinol (Lausanne)
Main Authors: Ropolo, Alejandro, Catrinacio, Cintia, Renna, Felipe Javier, Boggio, Veronica, Orquera, Tamara, Gonzalez, Claudio D., Vaccaro, Maria I.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Endocrinology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324546/
https://ncbi.nlm.nih.gov/pubmed/32655498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00411
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