Improving the catalytic thermostability of Bacillus altitudinis W3 ω-transaminase by proline substitutions

As a green biocatalyst, transaminase with high thermostability can be better employed to synthesize many pharmaceutical intermediates in industry. To improve the thermostability of (R)-selective amine transaminase from Bacillus altitudinis W3, related mutation sites were determined by multiple amino...

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Detalles Bibliográficos
Publicado en:3 Biotech
Autores principales: Xie, Zihao, Zhai, Lixin, Meng, Di, Tian, Qiaopeng, Guan, Zhengbing, Cai, Yujie, Liao, Xiangru
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2020
Materias:
Short Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324462/
https://ncbi.nlm.nih.gov/pubmed/32656056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-020-02321-2
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