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Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation

Vaccination is a mainstay in preventive medicine, reducing morbidity and mortality from infection, largely by generating pathogen-specific neutralizing antibodies. However, standard immunization strategies are insufficient with increasing age due to immunological impediments, including defects in T...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Cao, Wenqiang, Fang, Fengqin, Gould, Timothy, Li, Xuanying, Kim, Chulwoo, Gustafson, Claire, Lambert, Simon, Weyand, Cornelia M., Goronzy, Jörg J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324201/
https://ncbi.nlm.nih.gov/pubmed/32452837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132417
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