Optimization, stabilization, and characterization of amphotericin B loaded nanostructured lipid carriers for ocular drug delivery

The current study sought to formulate, optimize, and stabilize amphotericin B (AmB) loaded PEGylated nanostructured lipid carriers (NLC) and to study its ocular biodistribution following topical instillation. AmB loaded PEGylated NLC (AmB-PEG-NLC) were fabricated by hot-melt emulsification followed...

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Veröffentlicht in:Int J Pharm
Hauptverfasser: Lakhani, Prit, Patil, Akash, Wu, Kai-Wei, Sweeney, Corinne, Tripathi, Siddharth, Avula, Bharathi, Taskar, Pranjal, Khan, Shabana, Majumdar, Soumyajit
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7323935/
https://ncbi.nlm.nih.gov/pubmed/31669555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2019.118771
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