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Δ(9)-Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure in Normotensive Rabbits
PURPOSE: Δ(9)-Tetrahydrocannabinol-valine-hemisuccinate, a hydrophilic prodrug of Δ(9)-tetrahydrocannabinol, synthesized with the aim of improving the ocular bioavailability of the parent molecule, was investigated in a lipid-based nanoparticle dosage form for ocular delivery. METHODS: Solid lipid n...
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| Publicat a: | Transl Vis Sci Technol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Association for Research in Vision and Ophthalmology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6753841/ https://ncbi.nlm.nih.gov/pubmed/31588378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.8.5.15 |
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