CD4(+) T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages

CD4(+) T cells may induce potent antitumor immune responses through interaction with antigen-presenting cells within the tumor microenvironment. Using a murine model of multiple myeloma, we demonstrated that adoptive transfer of idiotype-specific CD4(+) T cells may elicit curative responses against...

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Detalles Bibliográficos
Publicado en:Blood Adv
Autores principales: Haabeth, Ole Audun W., Hennig, Kjartan, Fauskanger, Marte, Løset, Geir Åge, Bogen, Bjarne, Tveita, Anders
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2020
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322971/
https://ncbi.nlm.nih.gov/pubmed/32544236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001434
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