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Identifying epigenetic biomarkers of established prognostic factors and survival in a clinical cohort of individuals with oropharyngeal cancer

BACKGROUND: Smoking status, alcohol consumption and HPV infection (acquired through sexual activity) are the predominant risk factors for oropharyngeal cancer and are thought to alter the prognosis of the disease. Here, we conducted single-site and differentially methylated region (DMR) epigenome-wi...

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Библиографические подробности
Опубликовано в: :Clin Epigenetics
Главные авторы: Langdon, Ryan, Richmond, Rebecca, Elliott, Hannah R., Dudding, Tom, Kazmi, Nabila, Penfold, Chris, Ingarfield, Kate, Ho, Karen, Bretherick, Andrew, Haley, Chris, Zeng, Yanni, Walker, Rosie M., Pawlita, Michael, Waterboer, Tim, Gaunt, Tom, Smith, George Davey, Suderman, Matthew, Thomas, Steve, Ness, Andy, Relton, Caroline
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322918/
https://ncbi.nlm.nih.gov/pubmed/32600451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00870-0
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