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Identifying epigenetic biomarkers of established prognostic factors and survival in a clinical cohort of individuals with oropharyngeal cancer

BACKGROUND: Smoking status, alcohol consumption and HPV infection (acquired through sexual activity) are the predominant risk factors for oropharyngeal cancer and are thought to alter the prognosis of the disease. Here, we conducted single-site and differentially methylated region (DMR) epigenome-wi...

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Détails bibliographiques
Publié dans:Clin Epigenetics
Auteurs principaux: Langdon, Ryan, Richmond, Rebecca, Elliott, Hannah R., Dudding, Tom, Kazmi, Nabila, Penfold, Chris, Ingarfield, Kate, Ho, Karen, Bretherick, Andrew, Haley, Chris, Zeng, Yanni, Walker, Rosie M., Pawlita, Michael, Waterboer, Tim, Gaunt, Tom, Smith, George Davey, Suderman, Matthew, Thomas, Steve, Ness, Andy, Relton, Caroline
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322918/
https://ncbi.nlm.nih.gov/pubmed/32600451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00870-0
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