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Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway

To investigate the mechanism dexmedetomidine in relieving the neurotoxicity of a developing brain induced by sevoflurane. Sprague-Dawley rats, 6 days old, were randomly divided into three groups. Rats in the control group were inhaled with air after injection of normal saline; rats in the sevofluran...

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Dades bibliogràfiques
Publicat a:Mediators Inflamm
Autors principals: Dong, Yunxia, Hong, Wei, Tang, Zhiyin, Gao, Yan, Wu, Xiuying, Liu, Hongtao
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322616/
https://ncbi.nlm.nih.gov/pubmed/32655312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5458061
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