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Loss of TrkB Signaling Due to Status Epilepticus Induces a proBDNF-Dependent Cell Death

Neurotrophins (NTs) are secretory proteins that bind to target receptors and influence many cellular functions, such as cell survival and cell death in neurons. The mammalian NT brain-derived neurotrophic factor (matBDNF) is the C-terminal mature form released by cleavage from the proBDNF precursor....

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Montroull, Laura Ester, Danelon, Víctor, Cragnolini, Andrea Beatriz, Mascó, Daniel Hugo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375841/
https://ncbi.nlm.nih.gov/pubmed/30800056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00004
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