Cabozantinib, a Multityrosine Kinase Inhibitor of MET and VEGF Receptors Which Suppresses Mouse Laser-Induced Choroidal Neovascularization

Choroidal neovascularization (CNV) is a leading cause of blindness in the elderly in developed countries and is particularly associated with age-related macular degeneration (AMD). Cabozantinib (CBZ) hinders the activation of multiple receptor tyrosine kinases involved in tumor angiogenesis, such as...

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Veröffentlicht in:J Ophthalmol
Hauptverfasser: Zhang, Xiaoli, Zhu, Manhui, Xie, Laiqing, Sun, Xiaodong, Xu, Jiaowen, Guo, Yang, Liu, Dong, Shi, Yunwei, Xu, Xun, Song, E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322600/
https://ncbi.nlm.nih.gov/pubmed/32655941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5905269
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