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VEGF-Production by CCR2-Dependent Macrophages Contributes to Laser-Induced Choroidal Neovascularization

Age-related macular degeneration (AMD) is the most prevalent cause of blindness in the elderly, and its exsudative subtype critically depends on local production of vascular endothelial growth factor A (VEGF). Mononuclear phagocytes, such as macrophages and microglia cells, can produce VEGF. Their p...

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Detalhes bibliográficos
Main Authors: Krause, Torsten A., Alex, Anne F., Engel, Daniel R., Kurts, Christian, Eter, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979804/
https://ncbi.nlm.nih.gov/pubmed/24714223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094313
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