Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease

Alzheimer's disease (AD) is an age-specific neurodegenerative disease that compromises cognitive functioning and impacts the quality of life of an individual. Pathologically, AD is characterised by abnormal accumulation of beta-amyloid (Aβ) and hyperphosphorylated tau protein. Despite research...

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Vydáno v:Neuropharmacology
Hlavní autoři: Joshi, Alok, Wang, Da-Hui, Watterson, Steven, McClean, Paula L., Behera, Chandan K., Sharp, Trevor, Wong-Lin, KongFatt
Médium: Artigo
Jazyk:Inglês
Vydáno: Pergamon Press 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322519/
https://ncbi.nlm.nih.gov/pubmed/32380022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2020.108118
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