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Glibenclamide inhibits BK polyomavirus infection in kidney cells through CFTR blockade

BK polyomavirus (BKPyV) is a ubiquitous pathogen in the human population that is asymptomatic in healthy individuals, but can be life-threatening in those undergoing kidney transplant. To-date, no vaccines or anti-viral therapies are available to treat human BKPyV infections. New therapeutic strateg...

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Publicat a:Antiviral Res
Autors principals: Panou, Margarita-Maria, Antoni, Michelle, Morgan, Ethan L., Loundras, Eleni-Anna, Wasson, Christopher W., Welberry-Smith, Matthew, Mankouri, Jamel, Macdonald, Andrew
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322401/
https://ncbi.nlm.nih.gov/pubmed/32229236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104778
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