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NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands

Saliva plays an essential role in the maintenance of oral health. The oral cavity environment changes during aging mainly due to alterations in the secretion and composition of saliva. In particular, unstimulated basal salivary flow decreases with age. The functional decline of the salivary glands i...

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Détails bibliographiques
Publié dans:Redox Biol
Auteurs principaux: Wati, Sisca Meida, Matsumaru, Daisuke, Motohashi, Hozumi
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322188/
https://ncbi.nlm.nih.gov/pubmed/32590331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101603
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