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Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss

Age-related hearing loss (AHL) is a progressive sensorineural hearing loss in elderly people. Although no prevention or treatments have been established for AHL, recent studies have demonstrated that oxidative stress is closely related to pathogenesis of AHL, suggesting that suppression of oxidative...

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Detalhes bibliográficos
Publicado no:NPJ Aging Mech Dis
Main Authors: Oishi, Tetsuya, Matsumaru, Daisuke, Ota, Nao, Kitamura, Hiroshi, Zhang, Tianxiang, Honkura, Yohei, Katori, Yukio, Motohashi, Hozumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736866/
https://ncbi.nlm.nih.gov/pubmed/33318486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41514-020-00053-4
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