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Peripheral myelin protein 22 preferentially partitions into ordered phase membrane domains

The ordered environment of cholesterol-rich membrane nanodomains is thought to exclude many transmembrane (TM) proteins. Nevertheless, some multispan helical transmembrane proteins have been proposed to partition into these environments. Here, giant plasma membrane vesicles (GPMVs) were employed to...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Marinko, Justin T., Kenworthy, Anne K., Sanders, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322011/
https://ncbi.nlm.nih.gov/pubmed/32513719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000508117
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