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Drug-Drug Interactions of Irinotecan, 5-Fluorouracil, Folinic Acid and Oxaliplatin and Its Activity in Colorectal Carcinoma Treatment

The combination of folinic acid, 5-fluorouracil, oxaliplatin and/or irinotecan (FOLFOXIRI) is the standard of care for metastatic colorectal cancer (CRC). This strategy inhibits tumor growth but provokes drug resistance and serious side effects. We aimed to improve FOLFOXIRI by optimization of the d...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Zoetemelk, Marloes, Ramzy, George M., Rausch, Magdalena, Nowak-Sliwinska, Patrycja
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321123/
https://ncbi.nlm.nih.gov/pubmed/32512790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25112614
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