Phase III Noninferiority Trial Comparing Irinotecan With Oxaliplatin, Fluorouracil, and Leucovorin in Patients With Advanced Colorectal Carcinoma Previously Treated With Fluorouracil: N9841

PURPOSE: The primary goal of this multicenter phase III trial was to determine whether overall survival (OS) of fluorouracil (FU) -refractory patients was noninferior when treated with second-line infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4; arm B) versus irinotecan (arm A). Cross-...

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Detalhes bibliográficos
Main Authors: Kim, George P., Sargent, Daniel J., Mahoney, Michelle R., Rowland, Kendrith M., Philip, Philip A., Mitchell, Edith, Mathews, Abraham P., Fitch, Tom R., Goldberg, Richard M., Alberts, Steven R., Pitot, Henry C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698019/
https://ncbi.nlm.nih.gov/pubmed/19380443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.20.4552
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