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debCAM: a bioconductor R package for fully unsupervised deconvolution of complex tissues

SUMMARY: We develop a fully unsupervised deconvolution method to dissect complex tissues into molecularly distinctive tissue or cell subtypes based on bulk expression profiles. We implement an R package, deconvolution by Convex Analysis of Mixtures (debCAM) that can automatically detect tissue/cell-...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Chen, Lulu, Wu, Chiung-Ting, Wang, Niya, Herrington, David M, Clarke, Robert, Wang, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320609/
https://ncbi.nlm.nih.gov/pubmed/32219387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa205
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