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UNDO: a Bioconductor R package for unsupervised deconvolution of mixed gene expressions in tumor samples

Summary: We develop a novel unsupervised deconvolution method, within a well-grounded mathematical framework, to dissect mixed gene expressions in heterogeneous tumor samples. We implement an R package, UNsupervised DecOnvolution (UNDO), that can be used to automatically detect cell-specific marker...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Wang, Niya, Gong, Ting, Clarke, Robert, Chen, Lulu, Shih, Ie-Ming, Zhang, Zhen, Levine, Douglas A., Xuan, Jianhua, Wang, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271149/
https://ncbi.nlm.nih.gov/pubmed/25212756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu607
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