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Quantitative analysis of proteins which are members of the same protein complex but cause locus heterogeneity in disease

It is still largely unknown how mutations in different genes cause similar diseases – a condition known as locus heterogeneity. A likely explanation is that the different proteins encoded by the locus heterogeneity genes participate in the same biological function and, specifically, that they belong...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Gamba, Alessio, Salmona, Mario, Bazzoni, Gianfranco
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320193/
https://ncbi.nlm.nih.gov/pubmed/32591566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66836-7
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