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Quantitative analysis of proteins which are members of the same protein complex but cause locus heterogeneity in disease

It is still largely unknown how mutations in different genes cause similar diseases – a condition known as locus heterogeneity. A likely explanation is that the different proteins encoded by the locus heterogeneity genes participate in the same biological function and, specifically, that they belong...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Gamba, Alessio, Salmona, Mario, Bazzoni, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320193/
https://ncbi.nlm.nih.gov/pubmed/32591566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66836-7
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